The enforced international limitations and sanctions against Iran have affected all stages of natural gas extraction from gas reservoirs. In this study, the effects of various situations on natural gas extraction from the Iranian operating oil reservoirs have been examined. Thus, this study aimed to study the role and effects of imposed international sanctions on Iran’s gas extraction and production. Outcome of the study provides appropriate solutions to recognize such situation and cope with the resulting circumstances. Regarding methodology of the research, quantitative data were collected and analyzed by using the statistical panel model. Results show that gas extraction from natural gas reservoirs has been decreased significantly in the period of international sanctions and limitations were imposed. To achieve the previous desired gas extraction level according to the initial developing plans and the existing potentials as well as to be able to cope with hardship of international circumstances, it is necessary to improve implementation system of the respective projects, attain technological knowledge and take serious steps towards resilient economy to enhance the domestic abilities through knowledge-based advancement especially in producing strategic equipment and goods required by such a large scale projects while the existing internal rules and regulations should be reformed and be more flexible.